{"id":1354,"date":"2020-02-05T16:08:43","date_gmt":"2020-02-05T16:08:43","guid":{"rendered":"https:\/\/staging.theduff.co.uk\/?p=1354"},"modified":"2020-03-30T13:22:28","modified_gmt":"2020-03-30T13:22:28","slug":"oestradiol-levels-ivf","status":"publish","type":"post","link":"https:\/\/theduff.co.uk\/oestradiol-levels-ivf\/","title":{"rendered":"<strong>Oestradiol levels and IVF:<\/strong> what you need to know"},"content":{"rendered":"\n<p><strong>WHEN IT CAME TO RESEARCHING OESTRADIOL, IT PROBABLY TOOK ME LONGER <\/strong>to figure out the pronunciation of the word than anything else in this article \u2013 and I'm still a bit&nbsp;confused. All I know for sure is that the \u201co\u201d at the beginning should be ignored. <\/p>\n\n\n\n<p>You can probably go with any of the following and not be laughed out of the room: <\/p>\n\n\n\n<ul><li>ESS-trade-ee-yall<\/li><li>EEESS-trade-ee-yall<\/li><li>Ess-trad-AI-yall<\/li><\/ul>\n\n\n\n<p>Oestradiol is already a minefield, and I haven\u2019t even got beyond the word itself yet. <\/p>\n\n\n\n<p>Let's move on&#8230; <\/p>\n\n\n<style>.elementor-572 .elementor-element.elementor-element-189190b1{padding:0% 36% 8% 22%;}.elementor-572 .elementor-element.elementor-element-6b407887 > .elementor-element-populated{margin:0% 3.2% 0% 14%;--e-column-margin-right:3.2%;--e-column-margin-left:14%;}.elementor-572 .elementor-element.elementor-element-65191d58{--box-background-color:#FCFAEE;--box-border-color:#007595;--box-border-width:0px;--box-border-radius:0px;--box-padding:24px;--box-min-height:48vh;--header-color:#F16653;--toggle-button-color:#333333;--item-text-color:#007595;--item-text-decoration:underline;--item-text-hover-decoration:underline;--marker-color:#007595;}.elementor-572 .elementor-element.elementor-element-65191d58 .elementor-toc__header, .elementor-572 .elementor-element.elementor-element-65191d58 .elementor-toc__header-title{font-size:20px;}.elementor-572 .elementor-element.elementor-element-65191d58 .elementor-toc__list-item{font-size:20px;}.elementor-572 .elementor-element.elementor-element-65191d58 > .elementor-widget-container{margin:0px 0px 0px 4px;}@media(max-width:1024px){.elementor-572 .elementor-element.elementor-element-189190b1{padding:0% 4% 10% 14%;}.elementor-572 .elementor-element.elementor-element-6b407887 > .elementor-element-populated{margin:0% 10% 0% 0%;--e-column-margin-right:10%;--e-column-margin-left:0%;padding:0px 0px 0px 0px;}}@media(max-width:767px){.elementor-572 .elementor-element.elementor-element-189190b1{margin-top:16%;margin-bottom:18%;padding:0% 0% 0% 0%;}.elementor-572 .elementor-element.elementor-element-6b407887 > .elementor-element-populated{margin:0% 0% 0% 0%;--e-column-margin-right:0%;--e-column-margin-left:0%;padding:0% 0% 0% 0%;}.elementor-572 .elementor-element.elementor-element-65191d58 > .elementor-widget-container{margin:0px 0px 0px 0px;padding:0px 0px 0px 0px;}}\/* Start custom CSS for table-of-contents, class: .elementor-element-65191d58 *\/.elementor-toc__header-title {\n    color: #333333;\n}\n\n.elementor-toc__list-wrapper {\n    margin: 0em 2em 2em 0em;\n}\n\n.elementor-toc__list-items--collapsible li:not(:last-of-type) {\n    margin: 1.5em 0em;\n    padding-bottom: 1.5em;\n    border-bottom: 0.5px solid #007595;\n}\n\n\/* --- For Mobile --- *\/\n@media only screen and (max-width: 400px) {\n    .elementor-toc__list-wrapper {\n    margin: -1em 0em 0em 0em;\n}\n\n.elementor-toc__list-items--collapsible li:not(:last-of-type) {\n    margin: 1.2em 0em;\n    padding-bottom: 1.2em;\n    border-bottom: 0.5px solid #007595;\n}\n}\/* End custom CSS *\/<\/style>\t\t<div data-elementor-type=\"section\" data-elementor-id=\"572\" class=\"elementor elementor-572\" data-elementor-post-type=\"elementor_library\">\n\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-189190b1 elementor-section-stretched elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"189190b1\" data-element_type=\"section\" data-settings=\"{&quot;stretch_section&quot;:&quot;section-stretched&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-6b407887\" data-id=\"6b407887\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-65191d58 elementor-toc--minimized-on-none elementor-widget elementor-widget-table-of-contents\" data-id=\"65191d58\" data-element_type=\"widget\" data-settings=\"{&quot;exclude_headings_by_selector&quot;:[],&quot;collapse_subitems&quot;:&quot;yes&quot;,&quot;min_height&quot;:{&quot;unit&quot;:&quot;vh&quot;,&quot;size&quot;:48,&quot;sizes&quot;:[]},&quot;headings_by_tags&quot;:[&quot;h2&quot;],&quot;minimized_on&quot;:&quot;none&quot;,&quot;marker_view&quot;:&quot;bullets&quot;,&quot;icon&quot;:{&quot;value&quot;:&quot;fas fa-circle&quot;,&quot;library&quot;:&quot;fa-solid&quot;},&quot;minimize_box&quot;:&quot;yes&quot;,&quot;hierarchical_view&quot;:&quot;yes&quot;,&quot;min_height_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;min_height_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"table-of-contents.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-toc__header\">\n\t\t\t<h4 class=\"elementor-toc__header-title\">\n\t\t\t\tContents\t\t\t<\/h4>\n\t\t\t\t\t\t\t<div class=\"elementor-toc__toggle-button elementor-toc__toggle-button--expand\" role=\"button\" tabindex=\"0\" aria-controls=\"elementor-toc__65191d58\" aria-expanded=\"true\" aria-label=\"Open table of contents\"><i aria-hidden=\"true\" class=\"fas fa-chevron-down\"><\/i><\/div>\n\t\t\t\t<div class=\"elementor-toc__toggle-button elementor-toc__toggle-button--collapse\" role=\"button\" tabindex=\"0\" aria-controls=\"elementor-toc__65191d58\" aria-expanded=\"true\" aria-label=\"Close table of contents\"><i aria-hidden=\"true\" class=\"fas fa-chevron-up\"><\/i><\/div>\n\t\t\t\t\t<\/div>\n\t\t<div id=\"elementor-toc__65191d58\" class=\"elementor-toc__body elementor-toc__list-items--collapsible\">\n\t\t\t<div class=\"elementor-toc__spinner-container\">\n\t\t\t\t<i class=\"elementor-toc__spinner eicon-animation-spin eicon-loading\" aria-hidden=\"true\"><\/i>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t<\/div>\n\t\t\n\n\n<h2 class=\"wp-block-heading\"><strong>What is oestradiol and what does it do? <\/strong><\/h2>\n\n\n\n<p>Oestradiol is a type of oestrogen, and it\u2019s a hormone that plays an important role during ovulation. It works alongside its best bud FSH (among other hormones) to deliver an egg into your ovary each month.<\/p>\n\n\n\n<p>Here\u2019s how it works during a \u201cnormal\u201d menstrual cycle: <\/p>\n\n\n\n<p><strong>1: FSH is released by the pituitary gland to stimulate the growth of the <a href=\"..\/follicle-egg-zygote-difference\/\">egg-containing follicles<\/a> in your ovaries<\/strong>. Lots of follicles will grow at the same time \u2013 and&nbsp;the cells around the eggs inside those follicles will produce oestradiol. This causes the lining of your uterus to thicken and prepare to receive the much-hoped-for fertilised egg in a couple of weeks\u2019 time. &nbsp;<\/p>\n\n\n\n<p><strong>2: Even though lots of follicles started to develop at the same time,&nbsp;there\u2019s just one super-impressive follicle that grows faster than all the others.<\/strong> It\u2019s known as the \u201cdominant follicle\u201d, and the cells around the egg in that follicle will produce a ton more oestradiol \u2013 which in turn&nbsp;sends a signal to decrease the amount of FSH being produced. The decrease in FSH has the effect of quieting all the other follicles, leaving only that one dominant follicle to continue growing. &nbsp;<\/p>\n\n\n\n<p><strong>3: Eventually, the egg inside the dominant follicle will be ready to be&nbsp;fertilised.<\/strong> But first, it needs to break free from its follicle and make its way to the fallopian tube \u2013 where the sperm can find it. &nbsp;<\/p>\n\n\n\n<p><strong>4: Re-enter stage left\u2026 oestradiol.<\/strong> Its level has been rising all this time, and right now we\u2019re at \u201cpeak oestradiol\u201d \u2013 which acts as a heads-up to the brain that the ovary is ready for the egg to be released. \u00a0<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-large\"><img fetchpriority=\"high\" decoding=\"async\" width=\"500\" height=\"429\" src=\"https:\/\/theduff.co.uk\/wp-content\/uploads\/2020\/03\/IVF-from-start-to-finish-02-e1583941866964.png\" alt=\"Menstrual cycle diagram showing oestradiol levels\" class=\"wp-image-1357\" srcset=\"https:\/\/theduff.co.uk\/wp-content\/uploads\/2020\/03\/IVF-from-start-to-finish-02-e1583941866964.png 500w, https:\/\/theduff.co.uk\/wp-content\/uploads\/2020\/03\/IVF-from-start-to-finish-02-e1583941866964-300x257.png 300w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/><\/figure><\/div>\n\n\n\n<p><strong>5: To get the process moving, the pituitary gland releases a high amount of another hormone called \u201cluteneising hormone\u201d (LH)<\/strong>, which acts as a heads-up to the ovary that \u201cIT\u2019S TIME TO RELEASE THE EGG!!!\u201d <\/p>\n\n\n\n<p><strong>6: The egg breaks free from the follicle and travels down to the fallopian tube<\/strong>, waiting to be fertilised.<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-large\"><img decoding=\"async\" width=\"500\" height=\"400\" src=\"https:\/\/theduff.co.uk\/wp-content\/uploads\/2020\/02\/IVF-from-start-to-finish-03-e1584027705166.png\" alt=\"Oocyte travelling through fallopian tube\" class=\"wp-image-782\" srcset=\"https:\/\/theduff.co.uk\/wp-content\/uploads\/2020\/02\/IVF-from-start-to-finish-03-e1584027705166.png 500w, https:\/\/theduff.co.uk\/wp-content\/uploads\/2020\/02\/IVF-from-start-to-finish-03-e1584027705166-300x240.png 300w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/><\/figure><\/div>\n\n\n\n<p>(Read this article on <a href=\"..\/menstrual-cycle-explained\/\">how \u201cnormal\u201d ovulation works<\/a> for the full and complete explanation of the entire process.)<\/p>\n\n\n\n<p>So that\u2019s what it is and what it does. Next up: what do we learn from measuring oestradiol levels? <\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>When do oestradiol levels get measured? <\/strong><\/h2>\n\n\n\n<p>You\u2019ll get your oestradiol level checked at two key points during the IVF process: <\/p>\n\n\n\n<ul><li>The first time is as part of your <a href=\"\/ivf-process-step-by-step\/\">day 3 baseline blood tests<\/a>&nbsp;before IVF starts. <\/li><li>The second time is throughout the \u201covarian stimulation\u201d phase of IVF. <a href=\"\/ivf-process-step-by-step\/\">Here\u2019s a complete overview of the IVF process<\/a>.<\/li><\/ul>\n\n\n\n<p>Some people also get their oestradiol level checked just before IVF starts. <\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Why do oestradiol levels get measured before IVF treatment?<\/strong><\/h2>\n\n\n\n<p>You\u2019ll get your oestradiol level checked as part of your <a href=\"\/ivf-process-step-by-step\/\">day 3 baseline blood tests<\/a>\u00a0along with your <a href=\"..\/fsh-levels-ivf\/\">FSH<\/a> and <a href=\"..\/amh-levels-ivf\/\">AMH<\/a> levels, and your <a href=\"..\/antral-follicle-count-ivf\/\">antral follicle count<\/a>. <\/p>\n\n\n\n<p>As with FSH and AMH (and your antral follicle count), your oestradiol level gives an indication of how many\u00a0<a href=\"..\/follicle-egg-zygote-difference\/\">egg-containing follicles<\/a> you have remaining in your ovaries \u2013 which is important for knowing your likelihood of getting pregnant and the type of\u00a0IVF protocol you should be put on. (More on this in the article on <a href=\"\/ivf-process-step-by-step\/\">the IVF proess from start to finish<\/a>.)<\/p>\n\n\n\n<p>Your level is calculated in a weird, roundabout kind of way. Here goes an explanation\u2026 <\/p>\n\n\n\n<p>On day 3 of your period (i.e. the third day of your bleed), your follicles shouldn\u2019t have matured or developed to the extent that they\u2019ve started to release oestradiol, so your oestradiol level should be low. If you have a high oestradiol level that early on, it indicates that something weird is going on with your ovaries. \u00a0<\/p>\n\n\n\n<p>The most likely \u201cweird\u201d thing concerns your <a href=\"..\/fsh-levels-ivf\/\">FSH level<\/a>. You see, your FSH level should also be low according to your day 3 blood tests: FSH stimulates your egg-containing follicles to grow, but only a minuscule amount of the stuff should be needed to do so. If you have a high level of FSH according to your blood tests, it means you\u2019re working extra hard to get your follicles to <em>bloomin\u2019 well start growing<\/em> \u2013 and that in turn\u00a0implies you don\u2019t have many eggs left (which makes it harder to get the ones remaining to respond to your requests). <\/p>\n\n\n\n<p>But even if your FSH is working like crazy to get some sort of&nbsp;egg growth, your blood tests <em>could <\/em>give you a misleadingly low FSH result. Why? Because high oestradiol levels artificially suppress FSH levels, which leads to the misleading FSH blood test result. (That is,&nbsp;your FSH is <em>actually <\/em>through the roof, but your oestradiol is disguising it as part of some \u201cwhen I go high, you go low\u201d pact they seem to have with each other.)<\/p>\n\n\n\n<p>SO (getting there, promise!)&#8230; if your FSH level looks to be reassuringly low but you\u2019re struggling to conceive, your high oestradiol level will signal that you\u2019ve all been had. <\/p>\n\n\n\n<p>The oestradiol blood test basically&nbsp;checks that the FSH blood test is telling you the truth. <\/p>\n\n\n\n<p>Another reason for an elevated oestradiol level is that you still have \u201cactive cysts\u201d remaining in your ovaries from previous cycles. The outer shell of a follicle remains after an egg has been released \u2013 and for a short time after ovulation, it continues to produce the hormones needed in case of pregnancy. If you start fertility treatment while these cysts are still around, it can mess up your fertility cycle.<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-large is-resized\"><img decoding=\"async\" src=\"https:\/\/theduff.co.uk\/wp-content\/uploads\/2020\/02\/Group-1285@2x.png\" alt=\"\" class=\"wp-image-492\" width=\"229\" height=\"105\" srcset=\"https:\/\/theduff.co.uk\/wp-content\/uploads\/2020\/02\/Group-1285@2x.png 443w, https:\/\/theduff.co.uk\/wp-content\/uploads\/2020\/02\/Group-1285@2x-300x137.png 300w\" sizes=\"(max-width: 229px) 100vw, 229px\" \/><\/figure><\/div>\n\n\n\n<p><\/p>\n\n\n<style>.elementor-291 .elementor-element.elementor-element-4c84a175{margin-top:2%;margin-bottom:12%;padding:1% 4% 1% 4%;z-index:2;}.elementor-291 .elementor-element.elementor-element-554afbfb > .elementor-element-populated{margin:0% 5% 0% 5%;--e-column-margin-right:5%;--e-column-margin-left:5%;}.elementor-291 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.elementor-element.elementor-element-68569f9a .elementor-button{font-size:0.8em;letter-spacing:0.2px;border-width:0px 60px 0px 60px;}.elementor-291 .elementor-element.elementor-element-68569f9a > .elementor-widget-container{margin:-4% 0% 10% 0%;padding:0px 0px 0px 0px;}.elementor-291 .elementor-element.elementor-element-4e68b04a{font-size:1em;}}\/* Start custom CSS for button, class: .elementor-element-144e6175 *\/#fdg {\n    color: #FFFFFF;\n}\n#fdg:hover {\n    color: #FFFFFF;\n}\/* End custom CSS *\/<\/style>\t\t<div data-elementor-type=\"section\" data-elementor-id=\"291\" class=\"elementor elementor-291\" data-elementor-post-type=\"elementor_library\">\n\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-4c84a175 elementor-section-stretched elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"4c84a175\" data-element_type=\"section\" id=\"Mailing-list-sign-up-box\" data-settings=\"{&quot;stretch_section&quot;:&quot;section-stretched&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-554afbfb\" data-id=\"554afbfb\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-21014cc2 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"21014cc2\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-7c412ba7\" data-id=\"7c412ba7\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-144e6175 elementor-align-center elementor-widget elementor-widget-button\" data-id=\"144e6175\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a class=\"elementor-button elementor-size-sm\" role=\"button\" id=\"fdg\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-text\">FREE DOWNLOAD<\/span>\n\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1ed2b9df elementor-widget elementor-widget-heading\" data-id=\"1ed2b9df\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<p class=\"elementor-heading-title elementor-size-default\">Questions to ask your doctor at every stage of IVF treatment: free downloadable guide<\/p>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-39ffc0a2 elementor-widget elementor-widget-text-editor\" data-id=\"39ffc0a2\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong>IVF isn\u2019t just overwhelming<\/strong>; it can also be a mind-boggling and sometimes terrifying experience because there\u2019s so much to learn and so many rules to follow.<\/p><p>Problem is, doctors are busy \u2013 and they often don\u2019t have the time to anticipate your concerns and provide all the information you might need.<\/p><p>This downloadable guide contains questions that will help you understand the process better, get the answers you deserve, and feel more in control of the situation (and your rights as a patient).<\/p><p><strong>Enter your email address to receive it right away.<\/strong><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-68569f9a elementor-mobile-button-align-center elementor-tablet-button-align-stretch elementor-button-align-stretch elementor-widget elementor-widget-form\" data-id=\"68569f9a\" data-element_type=\"widget\" data-settings=\"{&quot;button_width&quot;:&quot;20&quot;,&quot;button_width_mobile&quot;:&quot;100&quot;,&quot;button_width_tablet&quot;:&quot;25&quot;,&quot;step_next_label&quot;:&quot;Next&quot;,&quot;step_previous_label&quot;:&quot;Previous&quot;,&quot;step_type&quot;:&quot;number_text&quot;,&quot;step_icon_shape&quot;:&quot;circle&quot;}\" data-widget_type=\"form.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<form class=\"elementor-form\" method=\"post\" name=\"New Form\">\n\t\t\t<input type=\"hidden\" name=\"post_id\" value=\"291\"\/>\n\t\t\t<input type=\"hidden\" name=\"form_id\" value=\"68569f9a\"\/>\n\t\t\t<input type=\"hidden\" name=\"referer_title\" value=\"The Duff\" \/>\n\n\t\t\t\n\t\t\t<div class=\"elementor-form-fields-wrapper elementor-labels-\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-field-type-email elementor-field-group elementor-column elementor-field-group-email elementor-col-80 elementor-md-75 elementor-sm-100 elementor-field-required\">\n\t\t\t\t\t\t\t\t\t\t\t\t<label for=\"form-field-email\" class=\"elementor-field-label elementor-screen-only\">\n\t\t\t\t\t\t\t\tEmail\t\t\t\t\t\t\t<\/label>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<input size=\"1\" type=\"email\" name=\"form_fields[email]\" id=\"form-field-email\" class=\"elementor-field elementor-size-lg  elementor-field-textual\" placeholder=\"Your email address\" required=\"required\" aria-required=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<div class=\"elementor-field-group elementor-column elementor-field-type-submit elementor-col-20 e-form__buttons elementor-md-25 elementor-sm-100\">\n\t\t\t\t\t<button type=\"submit\" class=\"elementor-button elementor-size-lg\">\n\t\t\t\t\t\t<span >\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\" elementor-button-icon\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Get the PDF<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/button>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/form>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4e68b04a elementor-widget elementor-widget-text-editor\" data-id=\"4e68b04a\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong>I won't send you spam. Unsubscribe at any time.<\/strong><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t<\/div>\n\t\t\n\n\n<h2 class=\"wp-block-heading\"><strong>What oestradiol levels are considered \u201cgood\u201d (on pre-IVF blood tests)?<\/strong><\/h2>\n\n\n\n<p>There aren\u2019t any clear cutoff values for normal and abnormal oestradiol values, but doctors normally like to see anything between 92 and 294 pmol\/l. <\/p>\n\n\n\n<p>It\u2019s also possible to have an abnormally low oestradiol level. These are often associated with people who have PCOS or hypopituitarism. Women who have eating disorders or intense exercise regimes may also have a low level. Oh, and levels dip (and stay there) after menopause. <\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>What does it mean if I have a high oestradiol level (on pre-IVF blood tests)? <\/strong><\/h2>\n\n\n\n<p>It means the doctors need to take a deeper look at your other <a href=\"\/ivf-process-step-by-step\/\">day 3<\/a>&nbsp;test results to figure out what\u2019s going on. If you have a combination of high oestradiol and either high <a href=\"..\/fsh-levels-ivf\/\">FSH<\/a> or low <a href=\"..\/amh-levels-ivf\/\">AMH<\/a>, it indicates that there\u2019s a less-than-ideal number of eggs remaining in your ovaries \u2013 the cause of which is probably age-related. <\/p>\n\n\n\n<p>To understand the consequences of having a smaller number of eggs at the ready, this rather brilliant (if I do&nbsp;say so myself) article on <a href=\"..\/egg-quality-quantity-ovarian-reserve\/\">egg quality and egg quantity<\/a>&nbsp;will tell you everything you need to know. <\/p>\n\n\n\n<p>If the cause of your high level turns out to be an \u201cactive\u201d cyst (which will be confirmed with a scan), you may have to delay your IVF treatment until the cyst has disappeared. <\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Why do oestradiol levels get measured during IVF treatment?<\/strong><\/h2>\n\n\n\n<p>It\u2019s to make sure you\u2019re not about to fall off the ovarian hyperstimulation syndrome (OHSS) cliff. Basically, if your meds cause you to grow <em>too <\/em>many follicles, you\u2019re at risk of getting OHSS \u2013 which is a nasty&nbsp;nasty syndrome that\u2019s explained in more detail <a href=\"..\/ovarian-hyperstimulation-syndrome-ohss-ivf\/\">here<\/a>. <\/p>\n\n\n\n<p>As we already know, growing follicles produce oestradiol, so a super-high oestradiol level is an indicator that\u00a0you\u2019re producing too many of them. Your oestradiol level is used alongside your transvaginal ultrasound scans to determine just how many follicles there are. <\/p>\n\n\n\n<p><a href=\"\/ivf-process-step-by-step\/\">Read more about the entire IVF process here.<\/a><\/p>\n\n\n\n<p>Each large (>15mm) follicle will produce around 200\u2013500 pg\/ml of oestradiol. In an ideal world, IVF treatment will result in approximately 15\u201320 follicles (18\u201324mm), and an oestradiol level between 2,000 and 4,000 pg\/ml. Things get worrisome when you have more than 20 follicles (18\u201324mm), and an oestradiol level between 4,000 and 6,000 pg\/ml. Doctors do\u00a0<em>not\u00a0<\/em>like to see more than 30 follicles (18\u201324mm), and an oestradiol level above 6,000 pg\/ml.<\/p>\n\n\n\n<p>It's also possible to have a high oestradiol level without a large number of follicles \u2013 and that's still an indication that\u00a0you might get OHSS (although doctors aren't completely\u00a0sure why).\u00a0<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>What happens if I have a very high oestradiol level during IVF treatment? <\/strong><\/h2>\n\n\n\n<p>You <em>really <\/em>don\u2019t want to get OHSS, and the good news is that doctors have a few options for making sure you don\u2019t. Read all about them in this article on <a href=\"..\/ovarian-hyperstimulation-syndrome-ohss-ivf\/\">OHSS.<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Oestradiol levels: always the bridesmaid, never the bride<\/strong><\/h2>\n\n\n\n<p>OK that analogy didn\u2019t work (AT ALL), but the basic gist with oestradiol levels is that whenever we measure them, we always feel the need to measure something <em>else <\/em>at the same time \u2013 just to make sure we\u2019re getting an honest picture of what\u2019s going on. <\/p>\n\n\n\n<p>But if they\u2019re going to artificially suppress <a href=\"..\/fsh-levels-ivf\/\">FSH levels<\/a> like that, what can they expect? Exactly. 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.elementor-widget-container{margin:6% 0% 2% 0%;padding:0px 0px 0px 0px;}.elementor-291 .elementor-element.elementor-element-39ffc0a2{font-size:1em;}.elementor-291 .elementor-element.elementor-element-68569f9a .elementor-field-group .elementor-field, .elementor-291 .elementor-element.elementor-element-68569f9a .elementor-field-subgroup label{font-size:1em;}.elementor-291 .elementor-element.elementor-element-68569f9a .elementor-button{font-size:0.8em;letter-spacing:0.2px;border-width:0px 60px 0px 60px;}.elementor-291 .elementor-element.elementor-element-68569f9a > .elementor-widget-container{margin:-4% 0% 10% 0%;padding:0px 0px 0px 0px;}.elementor-291 .elementor-element.elementor-element-4e68b04a{font-size:1em;}}\/* Start custom CSS for button, class: .elementor-element-144e6175 *\/#fdg {\n    color: #FFFFFF;\n}\n#fdg:hover {\n    color: #FFFFFF;\n}\/* End custom CSS *\/<\/style>\t\t<div data-elementor-type=\"section\" data-elementor-id=\"291\" class=\"elementor elementor-291\" 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DOWNLOAD<\/span>\n\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1ed2b9df elementor-widget elementor-widget-heading\" data-id=\"1ed2b9df\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<p class=\"elementor-heading-title elementor-size-default\">Questions to ask your doctor at every stage of IVF treatment: free downloadable guide<\/p>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-39ffc0a2 elementor-widget elementor-widget-text-editor\" data-id=\"39ffc0a2\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong>IVF isn\u2019t just overwhelming<\/strong>; it can also be a mind-boggling and sometimes terrifying experience because there\u2019s so much to learn and so many rules to 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